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Nasaler High Flow

Literatur/ Studien über die Highflow-Therapie

The Use of High-flow Nasal Cannula in Patients with COVID-19


Bereich Kinderheilkunde:

Die Therapie erfolgte in den folgenden Studien über die Schnittstelle "Optiflow junior" Nasenbrille.


1. Research in high flow therapy: mechanisms of action.
Dysart, K., Miller, T.L., Wolfson, M.R., Shaffer, T.H. (2009)

2. High-flow nasal cannulae for respiratory support of preterm infants: a review of the evidence.
Manley, B.J., Dold, S.K., Davis. P.G., Roehr, C.C. (2012)


Studie: Infant Nasal High Flow: Clinical Paper Summaries

  • Dysart, K., Miller, T.L., Wolfson, M.R., Shaffer, T.H. in Respiratory Medicine 2009; 103: 1400-1405


Klinische Ergebnisse:

3.  A randomized controlled trial to compare heated humidified high-flow nasal cannulae with nasal continuous positive airway pressure postextubation in premature infants.
Collins C.L., Holberton J.R., Barfield C., Davis P.G. (2013)

4. High-flow nasal cannulae in very preterm infants after extubation.
Manley B.J., Owen L.S., Doyle L.W., Andersen C.C., Cartwright D.W., Pritchard M.A., Donath S.M., Davis P.G. (2013) 

5. High flow nasal cannulae therapy in infants with bronchiolitis.
McKiernan, C., Chua, L.C., Visintainer, P.F., Allen, H. (2010)

6. Reduced intubation rates for infants after introduction of high-flow nasal prong oxygen delivery.
Schibler, A., Pham, T.M., Dunster, K.R., Foster, K., Barlow, A., Gibbons, K., Hough, J.L. (2011)

7. High flow nasal cannula versus nasal CPAP for neonatal respiratory disease: a retrospective study.
Shoemaker, M.T., Pierce, M.R., Yoder, B.A., DiGeronimo, R.J. (2007)

8. Use of high-flow nasal cannula support in the emergency department reduces the need for intubation in pediatric acute respiratory insufficiency.
Wing, R., James, C., Maranda, L.S., Armsby, C.C. (2012)

9. Comparing two methods of delivering high-flow gas therapy by nasal cannula following endotracheal extubation: a prospective, randomized, masked, crossover trial.
Woodhead D.D., Lambert D.K., Clark J.M., Christensen R.D. (2006)

10. Heated, humidified high-flow nasal cannula versus nasal CPAP for respiratory support in neonates.
Yoder B.A., Stoddard R.A., Li M., King J., Dirnberger D.R., Abbasi S. (2013)

Physiologische Ergebnisse:

11. Nasopharyngeal airway pressures in bronchiolitis patients treated with high-flow nasal cannula oxygen therapy.
Arora B., Mahajan P., Zidan M.A., Sethuraman U. (2012)

12. Is treatment with a high flow nasal cannula effective in acute viral bronchiolitis? A physiologic study.
Milési C., Baleine J., Matecki S., Durand S., Combes C., Novais A.R., Cambonie G. (2013)

13. Pharyngeal pressure with high-flow nasal cannulae in premature infants.
Wilkinson D.J., Andersen C.C., Smith K., Holberton J. (2008)

14. Work of breathing using high-flow nasal cannula in preterm infants.
Saslow J.G., Aghai Z.H., Nakhla T.A., Hart J.J., Lawrysh R., Stahl G.E., Pyon K.H. (2006)

15. Effect of HFNC flow rate, cannula size, and nares diameter on generated airway pressures: an in vitro study.
Sivieri E.M., Gerdes J.S., Abbasi S.(2013)

Video: Optiflow Junior Fitting Guide (F&P Healthcare)

Bereich Erwachsenentherapie:


1. Research in high flow therapy: mechanisms of action.
Dysart K., Miller, T.L. Wolfson, M.R., Shaffer, T.H. (2009)

Spezielle Patientenstruktur:

2. Oxygen delivery through high-flow nasal cannulae increase end-expiratory lung volume and reduce respiratory rate in post-cardiac surgical patients.
Corley A., Caruana L.R., Barnett A.G., Tronstad O., Fraser J.F. (2011)

3. Humidified high flow nasal oxygen during respiratory failure in the emergency department: feasibility and efficacy.
Lenglet H., Sztrymf B., Leroy C., Brun P., Dreyfuss D., Ricard J.D. (2012)

4. High-flow nasal interface improves oxygenation in patients undergoing bronchoscopy.
Lucangelo U., Vassallo F.G., Marras E., Ferluga M., Beziza E., Comuzzi L., Berlot G., Zin W.A. (2012)

5. A preliminary randomized controlled trial to assess effectiveness of nasal high-flow oxygen in intensive care patients.
Parke R.L., McGuinness S.P., Eccleston M.L. (2011)

6. High-flow nasal cannula therapy in do-not-intubate patients with hypoxemic respiratory distress.
Peters S.G., Holets S.R., Gay P.C. (2013)

7. The clinical utility of long-term humidification therapy in chronic airway disease.
Rea H., McAuley S., Jayaram L., Garrett J., Hockey H., Storey L., O'Donnell G., Haru L., Payton M., O'Donnell K. (2010)

8. High-flow oxygen therapy in acute respiratory failure.
Roca O., Riera J., Torres F., Masclans J.R. (2010)

9. Patients with New York Heart Association class III heart failure may benefit with high flow nasal cannula supportive therapy: high flow nasal cannula in heart failure.
Roca O., Pérez-Terán P., Masclans J.R., Pérez L., Galve E., Evangelista A., Rello J. (2013)

10. Beneficial effects of humidified high flow nasal oxygen in critical care patients: a prospective pilot study.
Sztrymf B., Messika J., Bertrand F., Hurel D., Leon R., Dreyfuss D., Ricard J.D. (2011)


11. High flow nasal oxygen generates positive airway pressure in adult volunteers.
Groves, N. & Tobin, A. (2007)

12. Domiciliary humidification improves lung mucociliary clearance in patients with bronchiectasis.
Hasani A., Chapman T.H., McCool D., Smith R.E., Dilworth J.P., Agnew J.E. (2008)

13. Nasal high-flow therapy delivers low level positive airway pressure.
Parke R., McGuinness S., Eccleston M. (2009)

14. The effects of flow on airway pressure during nasal high-flow oxygen therapy.
Parke R.L., Eccleston M.L., McGuinness S.P. (2011)

15. Evaluation of a humidified nasal high-flow oxygen system, using oxygraphy, capnography and measurement of upper airway pressures.
Ritchie J.E., Williams A.B., Gerard C., Hockey H. (2011)

Video: Anleitung MyAirvo 2 (engl.)

Video: Highflow Therapie mit dem MyAirvo (engl.)

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